Custom Purification

Special chemistry

Service

Vote

Ask for a quote

Presentation

DIVERCHIM does custom purification using preparative chromatography in liquid and supercritical phases.

Thanks to our wide range of stationary phases (chiral or achiral), DIVERCHIM offers many solutions to separate diastereoisomers or achiral compounds. With more than ten years of experience in custom purification, DIVERCHIM now revalorizes crude products and purifies feedstock as well as finished products.

Research, characterization and quantification of batches impurities become more and more important for National Agencies for Medicines (FDA in the USA and ANSM in France). DIVERCHIM adapts to its customers’ requests and also offers its expertise in impurities isolation in order to characterize and validate them in the scope of validation methods used to quantify those substances.

In order to answer the needs and satisfy purification requests, DIVERCHIM has its own analytical equipment, allowing us to develop analytical methods and to scale them up.

OUR ANALYTICAL EQUIPMENT

2 Alliance HPLC 2695 (Waters®) with diode arrays
Acquity UPC² (Convergence chromatography SFC) (Waters®) with diode arrays
Alliance HPLC 2695/PDA/MS-ESI/Corona

OUR PURIFICATION EQUIPMENT

Thar SFC Prep 80 with UV/Vis detector (Waters®)
AutoPurification HPLC/MS System (Waters®) with diode array and mass spectrometry
Dynamax System (Varian®) with UV/Vis detector

OUR CHARACTERIZATION EQUIPMENT

Automatized 300 MHz RM Spectrometer (Brucker®)
Flash EA1112 elementary analyzer (Thermo Scientific®)
DSC1 Mettler Toledo® (-30°C to 450°): melting point determination
FT-IR Vector 22 (Brücker®)